Search results for "Membrane model"
showing 10 items of 11 documents
Reflexions on Mahler: Dessins, Modularity and Gauge Theories
2021
We provide a unified framework of Mahler measure, dessins d'enfants, and gauge theory. With certain physically motivated Newton polynomials from reflexive polygons, the Mahler measure and the dessin are in one-to-one correspondence. From the Mahler measure, one can construct a Hauptmodul for a congruence subgroup of the modular group, which contains the subgroup associated to the dessin. In brane tilings and quiver gauge theories, the modular Mahler flow gives a natural resolution of the inequivalence amongst the three different complex structures $\tau_{R,G,B}$. We also study how, in F-theory, 7-branes and their monodromies arise in the context of dessins. Moreover, we give a dictionary on…
On AdS7 stability
2019
AdS$_7$ supersymmetric solutions in type IIA have been classified, and they are infinitely many. Moreover, every such solution has a non-supersymmetric sister. In this paper, we study the perturbative and non-perturbative stability of these non-supersymmetric solutions, focusing on cases without orientifolds. Perturbatively, we first look at the KK spectrum of spin-2 excitations. This does not exhibit instabilities, but it does show that there is no separation of scales for either the BPS and the non-BPS case, thus proving for supersymmetric AdS$_7$ a well-known recent conjecture. We then use 7d gauged supergravity and a brane polarization computation to access part of the spectrum of KK sc…
Evaluation of the interaction and drug release from alpha,beta-polyaspartamide derivatives to a biomembrane model
2005
This article reports on a comparative study on the ability of various polymers, containing hydrophilic and/or hydrophobic groups, to interact with a biomembrane model using the differential scanning calorimetry (DSC) technique. Multilamellar vesicles of mixed dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidic acid (DMPA) were chosen as a model of cell membranes. The investigated samples were a water soluble polymer, the alpha,beta-poly(N-2-hydroxyethyl)-DL-aspartamide (PHEA) and its derivatives partially functionalized with polyethylene glycol (PEG2000) to obtain PHEA-PEG2000, with hexadecylamine (C16) to obtain PHEA-C16, and with both compounds to obtain PHEA-PEG2000-C16. Th…
Localization and Interactions of Melatonin in Cell Membrane Models
2005
Sensitivity and uncertainty analysis of an integrated ASM2d MBR model for wastewater treatment
2018
Abstract An integrated membrane bioreactor (MBR) model was previously proposed and tested. The model provides a comprehensive and detailed description of the nitrogen biological removal processes with respect to up-to-date literature. This paper presents a sensitivity and uncertainty analysis aimed at identifying the key factors affecting the variability of the model predictions. The Standardized Regression Coefficients (SRC) method was adopted for the sensitivity analysis. The uncertainty analysis was employed by running Monte Carlo simulations by varying only the value of the key factors affecting the model outputs. The sensitivity analysis combined with the uncertainty analysis applied h…
Interactions of tryptophan and serotonin with biomembrane models: Binding to reversed micellar systems of ionic and non ionic surfactants
2001
The interactions of Tryptophan (TRP) and Serotonin (5-HT), with water-containing sodium bis (2-ethylhexyl) sulfosuccinate (AOT), didodecyldimethylammonium bromide (DDAB) and tetraethylene glycol monododecyl ether (C12E4) reversed micelles have been investigated by UV absorption spectroscopy. Our results suggest that independently of the nature of the surfactant and the amount of the water encapsulated into the micellar core, TRP and 5-HT are solubilized in the micellar phase, preferring to be located in a shallow region constituted by the hydrated surfactant head groups. This is due to the amphiphilic nature of TRP and 5-HT and the biological implications are discussed.
A new integrated MBR model for wastewater treatment: sensitivity and uncertainty analysis
2017
In this study a new integrated membrane bioreactor (MBR) model is proposed. The model is able to describe the main biological processes aimed at the carbon and the nutrients (nitrogen, N and phosphorus, P) removal coupled with the soluble microbial products (SMP) formation/degradation. Furthermore, the model describes the key physical processes and the interconnection between SMP and membrane fouling. The model was calibrated by adopting data measured during the monitoring of a University Cape Town (UCT) MBR pilot plant. A sensitivity analysis allowed the reduction of the number of model FACTORs to be calibrated from 122 to 45. A good correlation between measured and simulated data was obta…
Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I)
2016
Four gold(I) carbene complexes featuring 4-ferro-cenyl-substituted imidazol-2-ylidene ligands were investigated for antiproliferative and antivascular properties. They were active against a panel of seven cancer cell lines, including multidrug-resistant ones, with low micromolar or nanomolar IC50 (72 h) values, according to their lipophilicity and cellular uptake. The delocalized lipophilic cationic complexes 8 and 10 acted by increasing the reactive oxygen species in two ways: through a genuine ferrocene effect and by inhibiting the thioredoxin reductase. Both complexes gave rise to a reorganization of the F-actin cytoskeleton in endothelial and melanoma cells, associated with a G1 phase c…
Spectrophotometric investigation of the binding of vitamin E to water-containing reversed micelles.
2002
The distribution constants of vitamin E partitioned between apolar organic phase and water-containing reversed micelles of sodium bis (2-ethylhexyl) sulfosuccinate (AOT), didodecyldimethylammonium bromide (DDAB), soybean phosphatidylcholine (lecithin) and tetraethylene glycol monododecyl ether (C12E4) have been evaluated by a spectrophotometric method. The results suggest that in the presence of domains from apolar organic solvent to surfactant and to water, vitamin E is partitioned between the micellar palisade layer and the organic solvent and also that its binding strength to reversed micelles depends mainly by specific interactions between the head group of vitamin E and that of the sur…
1H-NMR and FT-IR study of the state of melatonin confined in membrane models: location and interactions of melatonin in water free lecithin and AOT r…
2004
The state of melatonin confined either in dry lecithin or bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) reversed micelles has been investigated by H-1-NMR and FT-IR spectroscopies as a function of the melatonin to surfactant molar ratio (R). The analysis of experimental results leads to hypothesize that, independently of R and the surfactant nature and as a consequence of anisotropic melatonin/surfactant interactions, melatonin is totally solubilized in reversed micelles and mainly located by opportune orientation in the nanodomain constituted by the surfactant head groups. The absence of significant spectral changes related to the protons linked to the first carbon atoms of surfactant…